News Articles

The immunoregulator IDO1


Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first and rate-limiting step in the kynurenine pathway, which converts the essential amino acid tryptophan into kynurenine and other metabolites (Ball, 2014). This enzymatic activity exerts significant immunoregulatory effects, which has made it an attractive target for immunotherapy research...Read more

Multiplex tissue image of the month - AQP3 in kidney

News image of the month June 2024 AQP3 2.JPG

The difference in spatial distributions of two aquaporin proteins in the cells of collecting ducts in the kidney is illuminated through multiplex immunohistochemistry (mIHC/IF)...Read more

Csaba Adori receives the 2024 Lennart Nilsson Award


The neurobiologist Csaba Adori is awarded the 2024 Lennart Nilsson Award for his scientific 3D photography of tissues. The motivation states that he in the spirit of Lennart Nilsson combines the scientific aspects of tissue structure and its pathology, that contribute to the understanding of tissue anatomy, with the beauty of anatomical details revealed by artistic images...Read more

HPA keynote lecture at the ELIXIR-organized All-Hands-conference


The Director of the Human Protein Atlas program Mathias Uhlen delivered a keynote lecture entitled "HPA - implications for human biology, drug development and precision medicine" at the ELIXIR conference in Uppsala...Read more

Episomal stable pools in WAVE bioreactors for fast and robust protein production


Recombinant proteins are important resources in several stages of drug discovery as well as many other types of research. The amounts of pure protein required span from a few micrograms for immunisations to hundreds of milligrams or even grams for activity evaluations and structure determinations. Here a highly scalable process for protein production in CHO cells that generates robust product quality and high performance throughout scales is presented...Read more