News ArticlesReducing uncertainty in drug development: a Q&A with Thomas HelledayT cells are central drivers of inflammation across autoimmune and inflammatory diseases, yet current therapies inadequately target pathogenic T-cell pathways, limiting durable disease control. In a recent study published in Signal Transduction and Targeted Therapy, a team led by Thomas Helleday and Theodora Manolakou, identified a novel, targetable transcriptional-metabolic axis that sustains inflammatory T-cell responses. In an interview by Gustav Ceder, Helleday discusses the novel findings and ongoing lines of research...Read more Talking transcriptomicsIn this episode of Proteins Unfolded Evelina Sjöstedt, head of Single cell analysis at the Human Protein Atlas, joins the hosts PhD students Andrea Villanueva Raisman and Emilio Skarwan to explore the transcriptome, the bridge between our static DNA and active proteins...Read more The Proteomics Show with Cecilia LindskogIn the Episode 82 of of the Proteomics show podcast series "Alt Proteomics" HPA researcher Dr Cecilia Lindskog talks about the importance of proteomics data integration together with the hosts Benjamin Neely and Ben Orsburn...Read more HPA integrates cell type resolution protein data based on Deep Visual ProteomicsIn the new release version 25.1 of the Human Protein Atlas, a major dataset based on Deep Visual Proteomics has been integrated in the Single cell Resource to provide mass-spectrometry based proteomics at an unprecedented resolution for a large number of cell types and tissues...Read more Advancing tissue-based protein data through antibody collaborationsThe Human Protein Atlas is pleased to acknowledge GeneTex's recent press release announcing the formalization of a collaborative relationship with the Human Protein Atlas. This agreement supports our continued efforts to expand high-quality antibody-based characterization of the human proteome and make these data openly available to the scientific community...Read more |