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– GENE INFO –
Gene name
Protein class
Chromosome
External id
– DATA AVAILABILITY –
Has protein data
– DATA RELIABILITY –
Reliability score tissue (IHC)
Reliability score mouse brain
Reliability score cells (ICC)
– ANTIBODY VALIDATION –
Protein array (PA)
Western blot (WB)
Immunohistochemistry (IHC)
Immunocytochemistry (ICC)
– PRIMARY DATA –
Subcellular localization (ICC)
Tissue expression (IHC)
Tissue category (RNA)
Cell category (RNA)
Cancer category (RNA)
Tissue detectable (RNA)
Cell line detectable (RNA)
Cancer detectable (RNA)
Prognostic cancer
– PROTEIN EVIDENCE –
Evidence summary
UniProt evidence
HPA evidence
MS evidence
– ANTIBODIES –
With antibodies
– EXTRA –
Sort by
Term
Gene name
Class
Blood group antigen proteins
Cancer-related genes
Candidate cardiovascular disease genes
CD markers
Citric acid cycle related proteins
Disease related genes
Enzymes
FDA approved drug targets
G-protein coupled receptors
Mapped to UniProt SWISS-PROT
Nuclear receptors
Plasma proteins
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RAS pathway related proteins
Ribosomal proteins
RNA polymerase related proteins
Transcription factors
Transporters
Voltage-gated ion channels
Subclass
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
MT
Unmapped
X
Y
External id
In atlas
Tissue
Pathology
Cell
Reliability
Enhanced
Supported
Approved
Uncertain
Reliability
Supported
Approved
Reliability
Enhanced
Supported
Approved
Uncertain
Validation
Supported
Approved
Uncertain
Validation
Enhanced - Capture
Enhanced - Genetic
Enhanced - Independent
Enhanced - Orthogonal
Enhanced - Recombinant
Supported
Approved
Uncertain
Validation
Enhanced - Independent
Enhanced - Orthogonal
Supported
Approved
Uncertain
Validation
Enhanced - Genetic
Enhanced - Independent
Enhanced - Recombinant
Supported
Approved
Uncertain
Location
Actin filaments
Aggresome
Cell Junctions
Centrosome
Cleavage furrow
Cytokinetic bridge
Cytoplasmic bodies
Cytosol
Endoplasmic reticulum
Endosomes
Focal adhesion sites
Golgi apparatus
Intermediate filaments
Lipid droplets
Lysosomes
Microtubule ends
Microtubule organizing center
Microtubules
Midbody
Midbody ring
Mitochondria
Mitotic spindle
Nuclear bodies
Nuclear membrane
Nuclear speckles
Nucleoli
Nucleoli fibrillar center
Nucleoplasm
Nucleus
Peroxisomes
Plasma membrane
Rods & Rings
Vesicles
Searches
– RELIABILITY –
Enhanced
Supported
Approved
Uncertain
– SUBCELLULAR VARIATION –
Intensity variation
Spatial variation
Cell cycle intensity correlation
Cell cycle spatial correlation
Cell cycle biologically
Custom data cell cycle dependant
– MULTILOCALIZATION –
Multilocalizing
Localizing 1
Localizing 2
Localizing 3
Localizing 4
Localizing 5
Localizing 6
– OTHER –
Main location
Additional location
Tissue
Any
Adrenal gland
Appendix
Bone marrow
Breast
Bronchus
Caudate
Cerebellum
Cerebral cortex
Cervix, uterine
Choroid plexus
Colon
Duodenum
Endometrium 1
Endometrium 2
Epididymis
Esophagus
Eye
Fallopian tube
Gallbladder
Hair
Heart muscle
Hippocampus
Hypothalamus
Kidney
Lactating breast
Liver
Lung
Lymph node
Nasopharynx
Oral mucosa
Ovary
Pancreas
Parathyroid gland
Pituitary gland
Placenta
Prostate
Rectum
Retina
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Skin 1
Skin 2
Small intestine
Smooth muscle
Soft tissue 1
Soft tissue 2
Sole of foot
Spleen
Stomach 1
Stomach 2
Testis
Thymus
Thyroid gland
Tonsil
Urinary bladder
Vagina
Cell type
Expression
Not detected
Low
Medium
High
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Breast
Cerebral cortex
Cervix, uterine
Colon
Duodenum
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Kidney
Liver
Lung
Lymph node
Ovary
Pancreas
Parathyroid gland
Placenta
Prostate
Rectum
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid gland
Tonsil
Urinary bladder
Specificity
Tissue enriched
Group enriched
Tissue enhanced
Elevated
Expressed in all
Mixed
Not detected
Cell line
Any
A-431
A549
AF22
AN3-CA
ASC diff
ASC TERT1
BEWO
BJ
BJ hTERT+
BJ hTERT+ SV40 Large T+
BJ hTERT+ SV40 Large T+ RasG12V
CACO-2
CAPAN-2
Daudi
EFO-21
FHDF/TERT166
HaCaT
HAP1
HBEC3-KT
HBF TERT88
HDLM-2
HEK 293
HEL
HeLa
Hep G2
HHSteC
HL-60
HMC-1
HSkMC
HTCEpi
HTEC/SVTERT24-B
HTERT-HME1
HUVEC TERT2
K-562
Karpas-707
LHCN-M2
MCF7
MOLT-4
NB-4
NTERA-2
PC-3
REH
RH-30
RPMI-8226
RPTEC TERT1
RT4
SCLC-21H
SH-SY5Y
SiHa
SK-BR-3
SK-MEL-30
T-47d
THP-1
TIME
U-138 MG
U-2 OS
U-2197
U-251 MG
U-266/70
U-266/84
U-698
U-87 MG
U-937
WM-115
Specificity
Cell line enriched
Group enriched
Cell line enhanced
Elevated
Expressed in all
Mixed
Not detected
Cancer
Any
Breast cancer
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Specificity
Tissue enriched
Group enriched
Tissue enhanced
Elevated
Expressed in all
Mixed
Not detected
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Breast
Cerebral cortex
Cervix, uterine
Colon
Duodenum
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Kidney
Liver
Lung
Lymph node
Ovary
Pancreas
Parathyroid gland
Placenta
Prostate
Rectum
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Small intestine
Smooth muscle
Spleen
Stomach
Testis
Thyroid gland
Tonsil
Urinary bladder
Detectable
Yes
No
Cell line
Any
A-431
A549
AF22
AN3-CA
ASC diff
ASC TERT1
BEWO
BJ
BJ hTERT+
BJ hTERT+ SV40 Large T+
BJ hTERT+ SV40 Large T+ RasG12V
CACO-2
CAPAN-2
Daudi
EFO-21
FHDF/TERT166
HaCaT
HAP1
HBEC3-KT
HBF TERT88
HDLM-2
HEK 293
HEL
HeLa
Hep G2
HHSteC
HL-60
HMC-1
HSkMC
HTCEpi
HTEC/SVTERT24-B
HTERT-HME1
HUVEC TERT2
K-562
Karpas-707
LHCN-M2
MCF7
MOLT-4
NB-4
NTERA-2
PC-3
REH
RH-30
RPMI-8226
RPTEC TERT1
RT4
SCLC-21H
SH-SY5Y
SiHa
SK-BR-3
SK-MEL-30
T-47d
THP-1
TIME
U-138 MG
U-2 OS
U-2197
U-251 MG
U-266/70
U-266/84
U-698
U-87 MG
U-937
WM-115
Detectable
Yes
No
Cancer
Any
Breast cancer
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Detectable
Yes
No
Cancer
Breast cancer
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
Prognosis
Favourable
Unfavourable
Category
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Score
Evidence at protein level
Evidence at transcript level
No evidence
Antibodies
Yes
No
Column
gene
position
tissue specific score
prognostic
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C17orf75
TISSUE
CELL
PATHOLOGY
TISSUE ATLAS
PRIMARY DATA
MOUSE BRAIN
GENE/PROTEIN
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Mouse brain
MOUSE BRAIN TISSUE
Gene description
Chromosome 17 open reading frame 75
Human tissue RNA category
Expressed in all.
Mouse gene
ENSMUSG00000057181
(version 88)
Annotation summary
Positivity in cell bodies and dendrites of neurons in several brain areas.
Positive cells and structures
Soma and dendrite in neurons.
Reliability
Approved
FRONT
BACK
Human cerebral cortex
Piriform cortex, L2
Somatosensory cortex
Dentate gyrus
Inferior olivary nucleus
Mitral cell and external plexiform layer of the olfactory bulb
Protein
Relative fluorescence intensity
Mouse brain region
255
0
olfactory bulb, forebrain
Anterior olfactory nucleus (aon)
Granule cell layer (gro)
Internal plexiform layer (ipl)
Mitral cell layer (mi)
Glomerular layer (gl)
Rostral migratory stream (rms)
External plexiform layer (epl)
External plexiform layer of the accessory OB (epla)
Granule cell layer of the accessory OB (gra)
Glomerular layer of the accessory OB (gla)
basal forebrain, forebrain
Dorsal tenia tecta (dtt)
Caudate putamen (cpu)
Accumbens nucleus, core (acbc)
Accumbens nucleus, shell (acbsh)
Island of Calleja (icj)
Ventral pallidum (vp)
Medial septum (ms)
Nucleus of the vertical limb of the diagonal band (vdb)
Lateral septum (ls)
Nucleus of the horizontal limb of the diagonal band (hdb)
N/A
Globus pallidus (gp)
cerebral cortex, forebrain
Frontal association cortex (fra)
Motor cortex (m)
Cingulate cortex (cg)
Piriform cortex, L1 (pirl1)
Piriform cortex, L2 (pirl2)
Piriform cortex, L3 (pirl3)
Insular cortex (i)
Somatosensory cortex (s)
Retrosplenial granular cortex (rsg)
Parietal association cortex (p)
Entorhinal cortex (ent)
Visual cortex (v)
hippocampus, forebrain
Polymorph layer of the dentate gyrus (podg)
Molecular layer of the dentate gyrus (modg)
Granular dentate gyrus (grdg)
CA1 - oriens layer (ca1or)
CA1 - pyramidal layer (ca1py)
CA1 - radiatum layer (ca1ra)
CA2 - oriens layer (ca2or)
CA2 - pyramidal layer (ca2py)
CA2 - radiatum layer (ca2ra)
CA3 - oriens layer (ca3or)
CA3 - pyramidal layer (ca3py)
CA3 - radiatum layer (ca3ra)
Stratum lucidum (slu)
Lacunosum moleculare (lmol)
Subiculum (sub)
circumventricular organs, forebrain
Subfornical organ (sfo)
amygdala, forebrain
Nucleus of the lateral olfactory tract (lot)
N/A
Basal medial amygdaloid nucleus (bma)
Basal lateral amygdaloid nucleus (bla)
Cortical amygdala (aco)
Central amygdala (ce)
Medial amygdaloid nucleus (mea)
hypothalamus, interbrain
Dorsal tuberomammillary nucleus (dtm)
Mammillary nucleus (mn)
Periventricular hypothalamic nucleus (pe)
Supraoptic nucleus (so)
Tuberal nucleus (tu)
Ventral tuberomammillary nucleus (vtm)
Lateral preoptic area (lpo)
Medial preoptic area (mpo)
Suprachiasmatic nucleus (sch)
N/A
Paraventricular hypothalamic nucleus (pa)
Anterior hypothalamic area, central (ahc)
Ventral medial hypothalamic nucleus (vmh)
Arcuate nucleus (arc)
Peduncular part of lateral hypothalmus (plh)
Dorsal medial hypothalamic nucleus (dm)
circumventricular organs, interbrain
Subcommissural organ (sco)
N/A
Median eminence (me)
thalamus, interbrain
Medial geniculate nucleus (mg)
Parafascicular thalamic nucleus (pf)
Pregeniculate nucleus (pg)
Stria terminalis (st)
Zona incerta (zi)
Anterodorsal thalamic nucleus (ad)
Reticular thalamic nucleus (rt)
Vental anterior thalamic nucleus (va)
Medial habenular nucleus (mhb)
Laterodorsal thalamic area (ld)
Paraventricular thalamic nucleus (pv)
Central medial thalamic area (cm)
Ventral lateral thalamic area (vl)
N/A
Ventral medial thalamic area (vm)
Lateral habenulal nucleus (lhb)
Ventral posterior thalamus (vpt)
Anterior pretactal nucleus (apt)
Retromammillary nucleus (rm)
N/A
midbrain motor, midbrain
Substantia nigra, reticular (snr)
Periaquaductal grey (pag)
Interpeduncular nucleus (ip)
Mesencephalic retic form (mrt)
Red nucleus (r)
Oculomotor nucleus (3n)
Mesencephalic trigeminal nucleus (me5)
N/A
Ventral tegmental area (vta)
midbrain behavioral, midbrain
Substantia nigra, compact (snc)
Dorsal raphe nucleus (dr)
Median raphe nucleus (mnr)
midbrain sensory, midbrain
Superior colliculi (sc)
External cortical inferior colliculli (ecic)
cerebellum, hindbrain
Vestibulocerebellar nucleus (vecb)
N/A
Moleuclar layer of the cerebellum (cemol)
Purkinje layer of the cerebellum (cepur)
Granular layer of the cerebellum (cegr)
circumventricular organs, hindbrain
Medulla (ap)
pons, hindbrain
Barrington's nucleus (bar)
N/A
Koelliker-fuse nucleus (kf)
N/A
Motor tregiminal nucleus (5n)
Parabrachial nucleus (pbp)
Principle sensory trigeminal nucleus (pr5)
Locus coeruleus (lc)
N/A
Pontine nucleus (pn)
Vestibular nucleus (ve)
Pontine reticular nucleus, oral (pno)
N/A
Lateral lemniscus (ll)
Superior paraolivary nucleus (spo)
medulla, hindbrain
Nucleus of the solitary tract (sol)
Raphe magnus nucleus (rmg)
N/A
Cochlear nucleus (cn)
N/A
Lateral paragigantocellular nucleus (lpg)
N/A
Raphe pallidus nucleus (rpa)
Facial nucleus (7n)
N/A
Hypoglossal nucleus (12n)
Ambiguus nucleus (amb)
External cuneate nucleus (ecu)
Inferior olivary nucleus (io)
Raphe obscures nucleus (rob)
Dorsal motor nucleus of vagus (10n)
Antibodies in assay
i
The internal antibody ID for the antibody/antibodies used for this specific target, click link for more antibody information.
HPA004061