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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Cells in tubules: 60 Cells in glomeruli: 20 Fibroblasts: 5 Other cell types: 15
Female, age 67
Sample 2 TPM: 11625.9
Cell types%
Cells in tubules: 70 Cells in glomeruli: 15 Fibroblasts: 10 Other cell types: 5
Female, age 55
Sample 3 TPM: 2390.4
Cell types%
Cells in tubules: 80 Cells in glomeruli: 10 Fibroblasts: 5 Other cell types: 5
Male, age 46
Sample 4 TPM: 12091.7
Cell types%
Cells in tubules: 60 Cells in glomeruli: 25 Fibroblasts: 5 Other cell types: 10
Female, age 57
Sample 5 TPM: 7610
Cell types%
Cells in tubules: 60 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 20
Male, age 78
Sample 6 TPM: 11436
Cell types%
Cells in tubules: 65 Cells in glomeruli: 10 Fibroblasts: 5 Other cell types: 20
Male, age 73
Sample 7 TPM: 21548.4
Cell types%
Cells in tubules: 60 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 20
Female, age 59
Sample 8 TPM: 11701.9
Cell types%
Cells in tubules: 65 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 15
Female, age 48
Sample 9 TPM: 13625.7
Cell types%
Cells in tubules: 60 Cells in glomeruli: 5 Fibroblasts: 10 Other cell types: 25
KIDNEY - GTEx RNA-seqi
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 9673.7
Min RPKM: 117.5
Std RPKM: 2615.7
Median RPKM: 2641.3
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
9673.7
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
9319.2
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
7889.3
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
7190.7
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
6430.8
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
5481.4
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
4875.3
GTEX-N7MS-1626-SM-3LK5F
60-69 years, male
4236.8
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
4128.1
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
3935.7
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
3877.3
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
3846.8
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
3814.6
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
3262.3
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
2767.0
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
2683.7
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
2598.8
GTEX-UPIC-1126-SM-4IHLO
20-29 years, female
2537.6
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
2103.1
GTEX-QLQW-1626-SM-4R1K1
30-39 years, male
1768.7
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
1742.9
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
1713.1
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
1288.6
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
1001.0
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
907.6
GTEX-12696-0926-SM-5FQTV
60-69 years, male
661.3
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
401.7
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
383.1
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
339.5
GTEX-ZYFD-1526-SM-5NQ7T
50-59 years, male
311.9
GTEX-13112-2126-SM-5GCO4
50-59 years, male
251.9
GTEX-RN64-1626-SM-48FD7
50-59 years, male
117.5
Show all
KIDNEY - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.
The Human Protein Atlas project is funded
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