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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA004179
A majority of normal tissues showed moderate to strong cytoplasmic staining, often granular. The liver, islet cells, glial cells, lymphoid tissues and myocytes were weakly stained or negative.
HPA007235
Normal tissues generally displayed moderate to strong cytoplasmic immunoreactivity, in some cases accompanied with nuclear staining. Hepatocytes, glial cells and stromal cells were in general negative.
HPA008855
Strong membranous immunoreactivity was observed in gastrointestinal tract, gall bladder, fallopian tube, placental trophoblasts and cervical glands. Germinal center cells in lymphoid tissues showed strong cytoplasmic positivity. Cells in CNS, hepatocytes and islets of Langerhans were negative. Remaining normal tissues showed weak to moderate cytoplasmic and/or membranous staining.
CAB000036
Strong cytoplasmic and membranous positivity in a majority of glandular epithelial cells. Liver, CNS, mesenchymal and inflammatory cells were negative.
CAB001986
Luminal membranes in a number of tissues, e.g. gastric mucosa, gall bladder, cervix and endometrium showed moderate immunoreactivity. Alveolar cells type II in lung and distal tubules in kidney displayed moderate cytoplasmic positivity.
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