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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody HPA046055
Glial cells
Not detected
Neuronal cells
Medium
Neuronal projections
High
Synapses
Not detected
Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody HPA061884
Glial cells
Not detected
Neuronal cells
Medium
Neuronal projections
High
Synapses
Not detected
HYPOTHALAMUS - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 6348.2
Min RPKM: 0.4
Std RPKM: 992.6
Median RPKM: 30.5
GTEX-13NYB-0011-R8a-SM-5KM4R
40-49 years, male
6348.2
GTEX-12ZZX-0011-R8a-SM-5DUW8
40-49 years, female
4278.6
GTEX-Z93S-0011-R8a-SM-4RGNL
50-59 years, male
3759.7
GTEX-13N1W-0011-R8a-SM-5MR56
70-79 years, male
2710.9
GTEX-13RTJ-0011-R8b-SM-5O9DL
60-69 years, male
2677.3
GTEX-11ZTS-0011-R8a-SM-57WDI
60-69 years, female
2268.2
GTEX-1399T-0011-R8b-SM-5IJD8
60-69 years, male
2146.0
GTEX-N7MT-0011-R8a-SM-2I5GU
60-69 years, female
1804.1
GTEX-WZTO-0011-R8A-SM-4E3II
40-49 years, male
1671.1
GTEX-ZVZQ-0011-R8a-SM-51MR5
60-69 years, female
1360.3
GTEX-TSE9-0011-R8A-SM-3DB7R
60-69 years, female
1313.8
GTEX-13OVH-0011-R8b-SM-5MR35
70-79 years, male
1271.9
GTEX-NPJ7-0011-R8a-SM-2I3G2
60-69 years, female
1035.9
GTEX-ZDXO-0011-R8a-SM-4WWD7
60-69 years, male
1028.0
GTEX-X585-0011-R8A-SM-46MUX
50-59 years, male
754.9
GTEX-ZVT3-0011-R8b-SM-57WDJ
60-69 years, female
596.7
GTEX-T6MN-0011-R8A-SM-32QP3
50-59 years, male
531.7
GTEX-R55E-0011-R8A-SM-2TC66
20-29 years, male
485.7
GTEX-13OW8-0011-R8a-SM-5L3G5
60-69 years, male
416.3
GTEX-RU72-0011-R8A-SM-2TF61
50-59 years, female
383.7
GTEX-11ONC-0011-R8b-SM-5NQ87
60-69 years, male
354.8
GTEX-145LU-0011-R8b-SM-5PNZG
50-59 years, male
335.2
GTEX-PWO3-0011-R8A-SM-2I5GD
60-69 years, female
325.3
GTEX-13OW6-0011-R8a-SM-5L3GF
50-59 years, male
320.6
GTEX-13FLV-0011-R8a-SM-5LZZE
50-59 years, male
315.5
GTEX-YFC4-0011-R8a-SM-4SOK3
40-49 years, female
311.7
GTEX-144GL-0011-R8a-SM-5Q5B1
50-59 years, male
304.1
GTEX-13O3O-0011-R8b-SM-5LUAL
60-69 years, female
253.7
GTEX-13SLX-0011-R8b-SM-5PNWZ
50-59 years, female
248.9
GTEX-13X6I-0011-R8a-SM-5PNZF
60-69 years, male
247.8
GTEX-13NZ8-0011-R8b-SM-5KM48
60-69 years, female
232.1
GTEX-P44H-0011-R8A-SM-2XCEL
40-49 years, male
228.7
GTEX-1313W-0011-R8a-SM-5DUVM
50-59 years, female
209.5
GTEX-13G51-0011-R8b-SM-5LZZ4
60-69 years, male
204.7
GTEX-QVJO-0011-R8A-SM-447C7
60-69 years, female
201.5
GTEX-11H98-0011-R8a-SM-5NQ8V
50-59 years, male
201.0
GTEX-11GSP-0011-R8b-SM-5NQ79
60-69 years, female
177.7
GTEX-WWYW-0011-R8A-SM-3NB3S
50-59 years, female
162.6
GTEX-ZF28-0011-R8a-SM-4WWFW
60-69 years, male
142.9
GTEX-13QIC-0011-R8b-SM-5O9CV
60-69 years, female
126.1
GTEX-131XW-0011-R8a-SM-5DUWY
50-59 years, female
121.2
GTEX-WHSE-0011-R8A-SM-3P5Z1
20-29 years, male
70.6
GTEX-132Q8-0011-R8b-SM-5DUWX
60-69 years, male
60.6
GTEX-13PDP-0011-R8b-SM-5O9CS
60-69 years, male
60.2
GTEX-RVPU-0011-R8A-SM-5SI8I
50-59 years, male
56.9
GTEX-ZXG5-0011-R8a-SM-57WD1
60-69 years, male
45.9
GTEX-13OVL-0011-R8a-SM-5L3HH
50-59 years, male
37.8
GTEX-QVUS-0011-R8A-SM-3GAD7
60-69 years, female
32.3
GTEX-14ASI-0011-R8b-SM-5S2UB
60-69 years, male
28.7
GTEX-13SLW-0011-R8b-SM-5SI64
70-79 years, male
23.0
GTEX-ZAB4-0011-R8b-SM-4SOKF
40-49 years, male
21.2
GTEX-NPJ8-0011-R8a-SM-2HMLG
40-49 years, male
19.8
GTEX-11OF3-0011-R8b-SM-57WCS
60-69 years, male
18.8
GTEX-X4XX-0011-R8B-SM-46MWM
60-69 years, male
18.0
GTEX-13FXS-0011-R8a-SM-5J1MN
50-59 years, male
15.6
GTEX-XOTO-0011-R8A-SM-4B65J
50-59 years, male
15.2
GTEX-13JVG-0011-R8a-SM-5KM3E
60-69 years, male
14.2
GTEX-13O3Q-0011-R8b-SM-5KM2J
50-59 years, male
13.7
GTEX-R55F-0011-R8A-SM-2TF4F
50-59 years, male
13.7
GTEX-X4XY-0011-R8A-SM-46MVC
60-69 years, male
13.6
GTEX-12WSM-0011-R8a-SM-5DUWJ
60-69 years, male
11.7
GTEX-X261-0011-R8A-SM-4E3I5
50-59 years, male
11.5
GTEX-139TS-0011-R8a-SM-5J1NP
60-69 years, male
10.6
GTEX-147F4-0011-R8b-SM-5S2UN
50-59 years, male
10.0
GTEX-N7MS-0011-R8a-SM-2YUMK
60-69 years, male
8.7
GTEX-13IVO-0011-R8a-SM-5L3DY
70-79 years, male
8.0
GTEX-13CF2-0011-R8b-SM-5IJCX
60-69 years, male
7.6
GTEX-YJ89-0011-R8b-SM-4SOK8
60-69 years, male
7.6
GTEX-ZUA1-0011-R8b-SM-51MST
40-49 years, male
6.4
GTEX-131XH-0011-R8a-SM-5EGLL
50-59 years, male
4.3
GTEX-11WQK-0011-R8a-SM-5BC7C
50-59 years, male
4.0
GTEX-145LS-0011-R8b-SM-5PNXA
60-69 years, female
4.0
GTEX-13NYS-0011-R8a-SM-5MR5H
60-69 years, male
3.6
GTEX-13FLW-0011-R8b-SM-5J1MZ
50-59 years, male
3.1
GTEX-11WQC-0011-R8b-SM-57WCH
60-69 years, male
3.0
GTEX-13X6K-0011-R8b-SM-5PNZ4
60-69 years, female
3.0
GTEX-WVLH-0011-R8A-SM-3MJFC
50-59 years, male
3.0
GTEX-14753-0011-R8b-SM-5S2U1
60-69 years, male
2.8
GTEX-13NZA-0011-R8b-SM-5KM2Q
60-69 years, male
2.7
GTEX-1445S-0011-R8a-SM-5PNWX
60-69 years, male
2.5
GTEX-13OVJ-0011-R8b-SM-5L3FS
50-59 years, female
2.0
GTEX-13OW5-0011-R8a-SM-5L3GQ
60-69 years, male
1.9
GTEX-Q2AG-0011-R8A-SM-2HMK5
40-49 years, female
1.9
GTEX-13CIG-0011-R8b-SM-5LZX5
50-59 years, male
1.6
GTEX-S7SE-0011-R8A-SM-2XCDG
50-59 years, male
1.3
GTEX-T5JC-0011-R8A-SM-32PLM
20-29 years, male
1.2
GTEX-XMD1-0011-R8A-SM-4AT48
60-69 years, male
1.2
GTEX-13X6J-0011-R8b-SM-5PNUA
50-59 years, male
1.1
GTEX-NL3H-0011-R8a-SM-5S2VF
60-69 years, male
1.1
GTEX-NL4W-0011-R8a-SM-2I3G4
50-59 years, male
1.1
GTEX-13OW7-0011-R8b-SM-5L3HR
50-59 years, male
0.9
GTEX-11ZUS-0011-R8a-SM-5BC73
30-39 years, male
0.7
GTEX-13QJC-0011-R8b-SM-5S2U6
60-69 years, female
0.7
GTEX-QMR6-0011-R8A-SM-32PKJ
50-59 years, male
0.6
GTEX-145MH-0011-R8a-SM-5PNUL
50-59 years, male
0.5
GTEX-12WSA-0011-R8a-SM-5P9EX
60-69 years, male
0.4
Show all
HYPOTHALAMUS - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.