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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Cells in tubules: 60 Cells in glomeruli: 20 Fibroblasts: 5 Other cell types: 15
Female, age 67
Sample 2 TPM: 2.5
Cell types%
Cells in tubules: 70 Cells in glomeruli: 15 Fibroblasts: 10 Other cell types: 5
Female, age 55
Sample 3 TPM: 4.3
Cell types%
Cells in tubules: 80 Cells in glomeruli: 10 Fibroblasts: 5 Other cell types: 5
Male, age 46
Sample 4 TPM: 3
Cell types%
Cells in tubules: 60 Cells in glomeruli: 25 Fibroblasts: 5 Other cell types: 10
Female, age 57
Sample 5 TPM: 0.2
Cell types%
Cells in tubules: 60 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 20
Male, age 78
Sample 6 TPM: 0.8
Cell types%
Cells in tubules: 65 Cells in glomeruli: 10 Fibroblasts: 5 Other cell types: 20
Male, age 73
Sample 7 TPM: 0.9
Cell types%
Cells in tubules: 60 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 20
Female, age 59
Sample 8 TPM: 1.8
Cell types%
Cells in tubules: 65 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 15
Female, age 48
Sample 9 TPM: 0.3
Cell types%
Cells in tubules: 60 Cells in glomeruli: 5 Fibroblasts: 10 Other cell types: 25
KIDNEY - GTEx RNA-seqi
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 12.0
Min RPKM: 0.8
Std RPKM: 2.8
Median RPKM: 2.9
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
12.0
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
10.3
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
8.2
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
8.2
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
7.8
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
7.6
GTEX-UPIC-1126-SM-4IHLO
20-29 years, female
6.9
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
5.5
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
4.8
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
4.2
GTEX-12696-0926-SM-5FQTV
60-69 years, male
3.9
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
3.9
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
3.8
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
3.6
GTEX-13112-2126-SM-5GCO4
50-59 years, male
3.5
GTEX-QLQW-1626-SM-4R1K1
30-39 years, male
3.0
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
2.8
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
2.8
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
2.6
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
2.4
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
2.4
GTEX-RN64-1626-SM-48FD7
50-59 years, male
2.2
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
2.1
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
2.1
GTEX-ZYFD-1526-SM-5NQ7T
50-59 years, male
2.1
GTEX-N7MS-1626-SM-3LK5F
60-69 years, male
1.9
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
1.7
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
1.3
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
1.0
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
1.0
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
1.0
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
0.8
Show all
KIDNEY - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.
The Human Protein Atlas project is funded
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