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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody HPA077062
Neuronal cells
Medium
Glial cells
Not detected
Neuronal projections
High
Synapses
High
Antibody stainingi
This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Neuronal cells: 35 Glial cells and endothelial cells: 65
Male, age 70
Sample 3 TPM: 187.2
Cell types%
Neuronal cells: 35 Glial cells and endothelial cells: 65
CEREBRAL CORTEX - GTEx RNA-seqi
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 124.9
Min RPKM: 5.9
Std RPKM: 21.8
Median RPKM: 42.0
GTEX-11OF3-2926-SM-5HL78
60-69 years, male
124.9
GTEX-WL46-2926-SM-3LK82
50-59 years, male
102.4
GTEX-WHSE-3026-SM-3P5ZH
20-29 years, male
95.1
GTEX-Z93S-2926-SM-57WB9
50-59 years, male
86.7
GTEX-12ZZX-2926-SM-5GCOQ
40-49 years, female
83.4
GTEX-13FXS-3126-SM-5J2NN
50-59 years, male
81.9
GTEX-T5JC-2426-SM-3NMDB
20-29 years, male
78.0
GTEX-1313W-3126-SM-5LZUI
50-59 years, female
76.5
GTEX-WWYW-3126-SM-3NB39
50-59 years, female
74.2
GTEX-13FLW-1426-SM-5K7YE
50-59 years, male
72.0
GTEX-ZYFD-3026-SM-5E44C
50-59 years, male
71.2
GTEX-YFC4-3126-SM-5PNV6
40-49 years, female
70.2
GTEX-13OW6-3026-SM-5J2MI
50-59 years, male
69.5
GTEX-X585-3026-SM-46MWF
50-59 years, male
68.7
GTEX-WZTO-2926-SM-3NM9I
40-49 years, male
67.5
GTEX-13VXU-2926-SM-5LU5C
50-59 years, male
66.5
GTEX-WVLH-3026-SM-3MJG9
50-59 years, male
65.9
GTEX-X4XX-3026-SM-3NMB2
60-69 years, male
65.4
GTEX-14ASI-3026-SM-5S2PN
60-69 years, male
65.0
GTEX-PVOW-2526-SM-2XCF7
40-49 years, male
63.1
GTEX-13NYC-2826-SM-5K7WR
60-69 years, male
62.9
GTEX-145MH-3026-SM-5Q5DZ
50-59 years, male
62.1
GTEX-11DXY-3226-SM-5GIDE
60-69 years, male
61.8
GTEX-14BMV-3026-SM-5S2PQ
50-59 years, male
61.6
GTEX-13SLX-3126-SM-5S2Q5
50-59 years, female
60.9
GTEX-T6MN-2626-SM-32PMQ
50-59 years, male
60.7
GTEX-11ZUS-2926-SM-5FQSL
30-39 years, male
60.1
GTEX-111FC-3126-SM-5GZZ2
60-69 years, male
59.6
GTEX-11DXW-1126-SM-5H12Q
40-49 years, male
59.4
GTEX-13OVH-3026-SM-5MR4N
70-79 years, male
59.4
GTEX-UTHO-3026-SM-3GAFB
60-69 years, male
58.6
GTEX-ZUA1-3026-SM-59HJC
40-49 years, male
58.1
GTEX-13FHO-3026-SM-5J1O9
60-69 years, male
55.7
GTEX-145LS-3126-SM-5Q5BY
60-69 years, female
55.5
GTEX-RNOR-2326-SM-2TF4I
50-59 years, female
52.4
GTEX-XLM4-3026-SM-4AT6L
60-69 years, male
51.9
GTEX-13NYB-3026-SM-5IJD7
40-49 years, male
51.7
GTEX-12126-1026-SM-5P9JJ
20-29 years, male
51.6
GTEX-XOTO-3026-SM-4B65M
50-59 years, male
51.5
GTEX-YJ89-3026-SM-5IFJI
60-69 years, male
51.3
GTEX-131YS-3126-SM-5KLYT
60-69 years, female
50.5
GTEX-TSE9-3026-SM-3DB76
60-69 years, female
50.3
GTEX-11PRG-2926-SM-5987A
50-59 years, male
50.1
GTEX-QVJO-1426-SM-2S1QY
60-69 years, female
49.7
GTEX-T2IS-3026-SM-32QPM
20-29 years, female
48.5
GTEX-144GL-3026-SM-5Q5CW
50-59 years, male
47.8
GTEX-12WSC-3026-SM-5GCNF
50-59 years, male
47.7
GTEX-145MF-2726-SM-5O995
50-59 years, male
47.5
GTEX-12ZZY-3026-SM-5GCOU
60-69 years, male
47.1
GTEX-11NUK-2926-SM-5A5MD
50-59 years, male
47.0
GTEX-117XS-3026-SM-5N9CA
60-69 years, male
45.9
GTEX-13PL6-3126-SM-5LUAR
40-49 years, female
45.8
GTEX-13O3Q-2926-SM-5KM45
50-59 years, male
43.8
GTEX-13O3O-3126-SM-5KM3H
60-69 years, female
43.7
GTEX-ZAK1-3026-SM-5S2MJ
50-59 years, female
42.7
GTEX-1128S-2726-SM-5H12C
60-69 years, female
42.5
GTEX-NPJ8-1526-SM-2D7VU
40-49 years, male
42.2
GTEX-ZVT3-3026-SM-5E43N
60-69 years, female
41.9
GTEX-Y8DK-0826-SM-4TT3T
60-69 years, male
41.0
GTEX-11ONC-2926-SM-5P9JM
60-69 years, male
40.7
GTEX-13NYS-3126-SM-5KLYV
60-69 years, male
40.5
GTEX-Q2AG-2926-SM-2HMJ3
40-49 years, female
40.1
GTEX-ZAJG-3126-SM-5HL9J
50-59 years, female
40.1
GTEX-1192X-3126-SM-5N9BY
50-59 years, male
40.0
GTEX-QMR6-1426-SM-32PLA
50-59 years, male
39.7
GTEX-13OW8-2826-SM-5L3GC
60-69 years, male
39.5
GTEX-13FHP-3026-SM-5IJBS
50-59 years, male
39.2
GTEX-RU72-3026-SM-5SI7Y
50-59 years, female
38.6
GTEX-132Q8-3026-SM-5PNVG
60-69 years, male
38.4
GTEX-145MG-3026-SM-5RQJA
50-59 years, male
38.2
GTEX-11GS4-3126-SM-5A5LH
60-69 years, male
37.1
GTEX-12WSH-3026-SM-5CVNI
50-59 years, male
35.9
GTEX-Y111-2726-SM-4TT3N
50-59 years, male
35.4
GTEX-11OC5-0726-SM-5P9JK
60-69 years, male
33.7
GTEX-R55F-1326-SM-5S2V4
50-59 years, male
32.7
GTEX-13QIC-2926-SM-5J2NF
60-69 years, female
32.3
GTEX-14A5I-2926-SM-5Q5CQ
50-59 years, female
32.1
GTEX-QDT8-2926-SM-32PKC
30-39 years, female
31.3
GTEX-QVUS-2826-SM-3GADB
60-69 years, female
30.4
GTEX-12ZZZ-3026-SM-5BC67
60-69 years, male
29.7
GTEX-11EI6-3026-SM-5GZZO
60-69 years, male
28.9
GTEX-13X6J-3026-SM-5Q5CU
50-59 years, male
28.6
GTEX-11GSO-2926-SM-5HL73
60-69 years, male
28.5
GTEX-NPJ7-2726-SM-2I3FT
60-69 years, female
28.1
GTEX-1399T-3026-SM-5KLZC
60-69 years, male
27.8
GTEX-13S7M-3126-SM-5RQJQ
60-69 years, female
27.4
GTEX-ZZPT-3026-SM-5GZXH
50-59 years, male
27.2
GTEX-12ZZW-2926-SM-5LZUP
50-59 years, male
26.1
GTEX-OXRN-2426-SM-2I5EQ
50-59 years, male
25.1
GTEX-11NV4-2126-SM-5N9DS
60-69 years, male
24.2
GTEX-11WQK-3026-SM-5EQL6
50-59 years, male
24.0
GTEX-131XW-3126-SM-5LZUC
50-59 years, female
24.0
GTEX-N7MT-1126-SM-5SI7V
60-69 years, female
23.7
GTEX-1117F-3226-SM-5N9CT
60-69 years, female
23.5
GTEX-11O72-2926-SM-5BC4V
40-49 years, male
23.4
GTEX-13JUV-2926-SM-5LZX7
40-49 years, female
23.4
GTEX-13G51-3026-SM-5IJB8
60-69 years, male
22.0
GTEX-13OW7-3026-SM-5L3GY
50-59 years, male
20.1
GTEX-144FL-3026-SM-5O99C
50-59 years, male
19.5
GTEX-147GR-3026-SM-5S2ML
60-69 years, male
18.3
GTEX-11EMC-3226-SM-5EGKW
60-69 years, female
18.2
GTEX-ZE7O-3126-SM-5HL5X
50-59 years, female
17.8
GTEX-13X6K-2926-SM-5Q5D5
60-69 years, female
16.8
GTEX-12WSD-3126-SM-5HL7P
60-69 years, female
16.2
GTEX-139T8-1026-SM-5J2MC
60-69 years, male
15.6
GTEX-13JVG-3126-SM-5L3FH
60-69 years, male
15.0
GTEX-13PVQ-3026-SM-5SI93
50-59 years, male
14.0
GTEX-13IVO-2926-SM-5L3CZ
70-79 years, male
12.3
GTEX-13OVJ-2826-SM-5L3GW
50-59 years, female
12.0
GTEX-11GSP-3226-SM-5986O
60-69 years, female
8.7
GTEX-PWO3-0926-SM-2I5EY
60-69 years, female
7.9
GTEX-11TTK-2926-SM-5PNYP
60-69 years, female
7.3
GTEX-1445S-3026-SM-5O9BR
60-69 years, male
6.8
GTEX-12WSA-2926-SM-5EQ4D
60-69 years, male
5.9
Show all
Brain - Frontal Cortex (BA9) RPKM: 46.9
Samples: 108
Max RPKM: 108.0
Min RPKM: 2.9
Std RPKM: 25.9
Median RPKM: 51.8
GTEX-X585-0011-R10A-SM-46MUY
50-59 years, male
108.0
GTEX-12ZZX-0011-R10b-SM-5DUWK
40-49 years, female
100.7
GTEX-131XH-0011-R10a-SM-5EGLJ
50-59 years, male
97.9
GTEX-145MH-0011-R10b-SM-5PNUK
50-59 years, male
97.7
GTEX-WVLH-0011-R10A-SM-3MJFM
50-59 years, male
95.5
GTEX-WZTO-0011-R10B-SM-4E3KB
40-49 years, male
90.2
GTEX-NL3H-0011-R10A-SM-2I3E9
60-69 years, male
89.8
GTEX-Z93S-0011-R10a-SM-4RGNM
50-59 years, male
88.9
GTEX-QVJO-0011-R10A-SM-2S1QJ
60-69 years, female
87.5
GTEX-12WSE-0011-R10b-SM-5P9JV
20-29 years, male
87.3
GTEX-X4XX-0011-R10B-SM-46MWO
60-69 years, male
86.4
GTEX-WWYW-0011-R10A-SM-3NB35
50-59 years, female
84.0
GTEX-13X6K-0011-R10a-SM-5P9JR
60-69 years, female
78.9
GTEX-13S7M-0011-R10b-SM-5PNZB
60-69 years, female
75.6
GTEX-WL46-0011-R10A-SM-3MJFQ
50-59 years, male
75.1
GTEX-Q2AG-0011-R10A-SM-2HMLA
40-49 years, female
74.1
GTEX-S7SE-0011-R10A-SM-2XCDF
50-59 years, male
72.4
GTEX-T6MN-0011-R10A-SM-32QP7
50-59 years, male
72.3
GTEX-YFC4-0011-R10a-SM-4SOK5
40-49 years, female
72.3
GTEX-145MG-0011-R10a-SM-5PNWG
50-59 years, male
72.0
GTEX-T5JC-0011-R10A-SM-32PM2
20-29 years, male
71.4
GTEX-NPJ8-0011-R10A-SM-2YUMO
40-49 years, male
68.8
GTEX-ZVZQ-0011-R10b-SM-51MRT
60-69 years, female
68.6
GTEX-12WSM-0011-R10a-SM-5DUWV
60-69 years, male
67.1
GTEX-1313W-0011-R10b-SM-5DUXA
50-59 years, female
65.9
GTEX-YJ89-0011-R10a-SM-4SOK9
60-69 years, male
63.3
GTEX-13OVL-0011-R10a-SM-5L3GS
50-59 years, male
63.2
GTEX-13N1W-0011-R10b-SM-5MR4H
70-79 years, male
62.1
GTEX-NPJ7-0011-R10A-SM-2I3E5
60-69 years, female
62.1
GTEX-13RTJ-0011-R10b-SM-5O9CW
60-69 years, male
61.6
GTEX-13X6I-0011-R10a-SM-5PNWI
60-69 years, male
61.2
GTEX-14ASI-0011-R10b-SM-5S2VZ
60-69 years, male
60.9
GTEX-13QIC-0011-R10a-SM-5O9C7
60-69 years, female
59.4
GTEX-13QJC-0011-R10a-SM-5SI63
60-69 years, female
58.6
GTEX-13FHO-0011-R10b-SM-5J2MM
60-69 years, male
58.5
GTEX-N7MS-0011-R10A-SM-2HMJK
60-69 years, male
58.5
GTEX-13CZV-0011-R10b-SM-5LZYD
60-69 years, male
57.7
GTEX-131YS-0011-R10b-SM-5EQ5N
60-69 years, female
57.1
GTEX-QDT8-0011-R10A-SM-32PKG
30-39 years, female
56.6
GTEX-N7MT-0011-R10A-SM-2I3E1
60-69 years, female
56.4
GTEX-ZF28-0011-R10a-SM-4WWEH
60-69 years, male
56.0
GTEX-14BIN-0011-R10a-SM-5S2UA
50-59 years, female
55.3
GTEX-XLM4-0011-R10A-SM-4AT5P
60-69 years, male
55.3
GTEX-13SLX-0011-R10a-SM-5P9HV
50-59 years, female
55.1
GTEX-13O3Q-0011-R10b-SM-5KM39
50-59 years, male
55.0
GTEX-13OW6-0011-R10a-SM-5L3HE
50-59 years, male
54.7
GTEX-Y8DK-0011-R10A-SM-4SOK1
60-69 years, male
54.4
GTEX-12WSC-0011-R10a-SM-5GU57
50-59 years, male
53.8
GTEX-145LS-0011-R10a-SM-5PNUQ
60-69 years, female
52.8
GTEX-13FLW-0011-R10b-SM-5LZZF
50-59 years, male
52.6
GTEX-12WSF-0011-R10a-SM-5LZVH
70-79 years, male
52.5
GTEX-13OW7-0011-R10a-SM-5L3H3
50-59 years, male
52.2
GTEX-132Q8-0011-R10b-SM-5DUWZ
60-69 years, male
52.0
GTEX-13X6J-0011-R10b-SM-5PNWA
50-59 years, male
51.8
GTEX-ZDXO-0011-R10a-SM-4WWD8
60-69 years, male
51.8
GTEX-12WSH-0011-R10a-SM-5LZUS
50-59 years, male
50.7
GTEX-147GR-0011-R10b-SM-5S2UM
60-69 years, male
50.7
GTEX-12ZZZ-0011-R10a-SM-5P9HC
60-69 years, male
50.6
GTEX-12ZZY-0011-R10b-SM-5HL7W
60-69 years, male
49.2
GTEX-13FXS-0011-R10a-SM-5J2MA
50-59 years, male
48.1
GTEX-11H98-0011-R10b-SM-5NQ98
50-59 years, male
41.1
GTEX-QMR6-0011-R10A-SM-32PKO
50-59 years, male
40.4
GTEX-ZVT3-0011-R10b-SM-57WB6
60-69 years, female
39.7
GTEX-13NYS-0011-R10a-SM-5MR4S
60-69 years, male
38.9
GTEX-14BIL-0011-R10a-SM-5SI75
50-59 years, male
38.1
GTEX-13NYB-0011-R10a-SM-5KM43
40-49 years, male
37.9
GTEX-13O3O-0011-R10a-SM-5LUA9
60-69 years, female
37.9
GTEX-13FLV-0011-R10b-SM-5LZZ2
50-59 years, male
33.7
GTEX-13JUV-0011-R10b-SM-5LZXR
40-49 years, female
33.6
GTEX-12126-0011-R10b-SM-5BC6T
20-29 years, male
33.4
GTEX-13G51-0011-R10b-SM-5LZYF
60-69 years, male
32.5
GTEX-ZXG5-0011-R10a-SM-57WDD
60-69 years, male
32.3
GTEX-ZAB4-0011-R10a-SM-4SOKH
40-49 years, male
31.7
GTEX-OXRN-0011-R10A-SM-2I5GC
50-59 years, male
31.2
GTEX-TSE9-0011-R10A-SM-3DB7O
60-69 years, female
31.1
GTEX-147F4-0011-R10b-SM-5S2WC
50-59 years, male
28.9
GTEX-ZUA1-0011-R10a-SM-51MT6
40-49 years, male
28.3
GTEX-NL4W-0011-R10A-SM-2I3DY
50-59 years, male
27.2
GTEX-13OW8-0011-R10a-SM-5L3H6
60-69 years, male
24.7
GTEX-RVPU-0011-R10A-SM-2XCAH
50-59 years, male
24.7
GTEX-QVUS-0011-R10A-SM-3GIK3
60-69 years, female
24.3
GTEX-145LU-0011-R10a-SM-5PNWJ
50-59 years, male
23.7
GTEX-P44H-0011-R10A-SM-2XCEK
40-49 years, male
23.3
GTEX-X4EP-0011-R10B-SM-4QASJ
60-69 years, female
23.3
GTEX-13SLW-0011-R10a-SM-5S2UI
70-79 years, male
22.4
GTEX-X261-0011-R10B-SM-4E3JT
50-59 years, male
22.3
GTEX-11WQC-0011-R10a-SM-57WCT
60-69 years, male
21.7
GTEX-139TS-0011-R10a-SM-5K7TU
60-69 years, male
20.7
GTEX-13FTZ-0011-R10b-SM-5KLZS
60-69 years, male
18.4
GTEX-11ZUS-0011-R10b-SM-5BC79
30-39 years, male
17.5
GTEX-ZE7O-0011-R10a-SM-57WAZ
50-59 years, female
16.8
GTEX-11WQK-0011-R10a-SM-5BC6R
50-59 years, male
15.9
GTEX-13NZA-0011-R10b-SM-5KM54
60-69 years, male
15.6
GTEX-12ZZW-0011-R10b-SM-5HL9X
50-59 years, male
14.6
GTEX-13N2G-0011-R10a-SM-5MR34
60-69 years, male
14.2
GTEX-13IVO-0011-R10a-SM-5LZY3
70-79 years, male
13.6
GTEX-XMD1-0011-R10A-SM-4AT4A
60-69 years, male
13.0
GTEX-12WSD-0011-R10b-SM-5GU79
60-69 years, female
11.7
GTEX-OXRO-0011-R10A-SM-2I5EH
60-69 years, female
10.1
GTEX-11GSP-0011-R10a-SM-5NQ7J
60-69 years, female
9.1
GTEX-13OVJ-0011-R10b-SM-5L3HT
50-59 years, female
8.3
GTEX-13JVG-0011-R10b-SM-5KM2P
60-69 years, male
7.3
GTEX-14753-0011-R10b-SM-5S2WE
60-69 years, male
7.0
GTEX-12WSA-0011-R10b-SM-5P9ET
60-69 years, male
6.2
GTEX-1477Z-0011-R10b-SM-5S2RF
60-69 years, male
5.7
GTEX-ZV68-0011-R10a-SM-51MT7
50-59 years, female
3.7
GTEX-131XW-0011-R10a-SM-5DUVA
50-59 years, female
3.3
GTEX-1445S-0011-R10a-SM-5PNWB
60-69 years, male
2.9
Show all
CEREBRAL CORTEX - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.