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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Hepatocytes: 80 Fibroblasts: 15 Other cell types: 5
Male, age 74
Sample 3 TPM: 40.2
Cell types%
Hepatocytes: 85 Fibroblasts: 5 Other cell types: 10
Female, age 62
Sample 4 TPM: 35.9
Cell types%
Hepatocytes: 70 Fibroblasts: 10 Other cell types: 20
Male, age 78
Sample 5 TPM: 36.2
Cell types%
Hepatocytes: 75 Fibroblasts: 5 Other cell types: 20
Male, age 53
Sample 6 TPM: 33.9
Cell types%
Hepatocytes: 80 Fibroblasts: 5 Other cell types: 15
Male, age 77
Sample 7 TPM: 42.4
Cell types%
Hepatocytes: 75 Fibroblasts: 5 Other cell types: 20
Female, age 72
Sample 8 TPM: 32.8
Cell types%
Hepatocytes: 50 Fibroblasts: 10 Other cell types: 40
Male, age 70
Sample 9 TPM: 28.7
Cell types%
Hepatocytes: 65 Fibroblasts: 10 Other cell types: 25
Female, age 23
Sample 10 TPM: 41.4
Cell types%
Hepatocytes: 70 Fibroblasts: 5 Other cell types: 25
LIVER - GTEx RNA-seqi
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 62.2
Min RPKM: 2.8
Std RPKM: 9.3
Median RPKM: 8.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
62.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
45.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
42.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
37.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
35.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
33.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
29.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
29.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
28.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
26.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
23.3
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
20.0
GTEX-S32W-1926-SM-4AD63
50-59 years, female
19.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
18.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
18.0
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
17.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
17.0
GTEX-Q734-0326-SM-48U15
40-49 years, female
16.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
15.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
15.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
15.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
14.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
13.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
13.6
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
13.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
13.2
GTEX-XOTO-0826-SM-4B65O
50-59 years, male
12.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
12.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
12.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
12.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
11.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
11.9
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
11.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
11.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
11.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
10.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
10.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
10.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
10.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
10.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
10.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
10.0
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
10.0
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
9.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
9.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
9.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
9.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
9.4
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
9.4
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
9.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
9.3
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
9.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
9.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
9.2
GTEX-YECK-1926-SM-4W21H
60-69 years, male
9.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
9.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
9.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
8.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
8.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
8.4
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
8.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
8.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
7.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
7.7
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
7.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
7.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
7.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
7.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
7.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
7.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
6.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
6.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
6.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
6.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
6.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
6.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
6.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
6.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
5.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
5.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
5.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
5.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
5.6
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
5.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
5.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
5.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
5.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
5.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
5.4
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
5.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
5.3
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
5.2
GTEX-UPIC-0926-SM-4IHLV
20-29 years, female
5.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
5.1
GTEX-ZF29-2026-SM-4WWB7
60-69 years, female
5.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
4.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
4.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
4.8
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
4.8
GTEX-QV44-0326-SM-4R1KD
50-59 years, male
4.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
4.7
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
4.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
4.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
4.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
4.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
4.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
4.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
4.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
4.1
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
4.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
4.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
3.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
3.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
3.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
3.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
3.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
2.8
GTEX-QEG4-1826-SM-4R1JN
30-39 years, male
2.8
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
2.8
Show all
LIVER - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.