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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Hepatocytes: 80 Fibroblasts: 15 Other cell types: 5
Male, age 74
Sample 3 TPM: 6.6
Cell types%
Hepatocytes: 85 Fibroblasts: 5 Other cell types: 10
Female, age 62
Sample 4 TPM: 2.1
Cell types%
Hepatocytes: 70 Fibroblasts: 10 Other cell types: 20
Male, age 78
Sample 5 TPM: 1.5
Cell types%
Hepatocytes: 75 Fibroblasts: 5 Other cell types: 20
Male, age 53
Sample 6 TPM: 6.9
Cell types%
Hepatocytes: 80 Fibroblasts: 5 Other cell types: 15
Male, age 77
Sample 7 TPM: 6.4
Cell types%
Hepatocytes: 75 Fibroblasts: 5 Other cell types: 20
Female, age 72
Sample 8 TPM: 8.1
Cell types%
Hepatocytes: 50 Fibroblasts: 10 Other cell types: 40
Male, age 70
Sample 9 TPM: 6.8
Cell types%
Hepatocytes: 65 Fibroblasts: 10 Other cell types: 25
Female, age 23
Sample 10 TPM: 6.5
Cell types%
Hepatocytes: 70 Fibroblasts: 5 Other cell types: 25
LIVER - GTEx RNA-seqi
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 52.6
Min RPKM: 11.6
Std RPKM: 7.9
Median RPKM: 29.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
52.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
52.0
GTEX-UPIC-0926-SM-4IHLV
20-29 years, female
50.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
48.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
47.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
47.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
44.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
43.5
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
43.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
42.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
41.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
41.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
40.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
39.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
39.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
38.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
38.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
38.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
37.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
37.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
36.4
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
36.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
35.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
35.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
35.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
35.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
35.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
35.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
34.9
GTEX-X261-1726-SM-4PQYT
50-59 years, male
34.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
34.5
GTEX-QESD-2026-SM-447BI
20-29 years, male
33.9
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
33.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
33.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
33.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
33.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
33.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
33.4
GTEX-ZF29-2026-SM-4WWB7
60-69 years, female
33.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
33.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
33.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
32.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
32.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
32.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
32.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
32.4
GTEX-RU72-1426-SM-46MUF
50-59 years, female
32.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
32.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
32.1
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
31.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
31.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
31.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
31.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
30.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
30.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
30.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
30.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
30.0
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
29.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
29.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
29.7
GTEX-YECK-1926-SM-4W21H
60-69 years, male
29.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
29.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
29.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
29.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
29.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
28.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
28.8
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
28.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
28.5
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
28.4
GTEX-QV44-0326-SM-4R1KD
50-59 years, male
28.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
27.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
27.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
27.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
27.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
27.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
27.0
GTEX-S32W-1926-SM-4AD63
50-59 years, female
27.0
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
26.8
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
26.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
26.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
26.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
26.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
25.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
25.8
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
25.7
GTEX-XOTO-0826-SM-4B65O
50-59 years, male
25.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
25.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
25.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
25.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
25.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
24.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
24.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
24.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
24.2
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
23.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
22.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
22.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
22.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
22.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
22.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
21.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
21.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
21.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
20.9
GTEX-QEG4-1826-SM-4R1JN
30-39 years, male
20.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
20.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
20.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
20.1
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
19.9
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
19.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
18.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
17.6
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
15.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
15.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
15.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
14.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
11.6
Show all
LIVER - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.