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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody HPA019472
Glial cells
Not detected
Neuronal cells
Not detected
Neuronal projections
High
Synapses
High
Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody CAB034105
Glial cells
Not detected
Neuronal cells
Not detected
Neuronal projections
High
Synapses
High
HYPOTHALAMUS - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 2299.9
Min RPKM: 5.2
Std RPKM: 346.9
Median RPKM: 183.0
GTEX-NL4W-0011-R8a-SM-2I3G4
50-59 years, male
2299.9
GTEX-R55F-0011-R8A-SM-2TF4F
50-59 years, male
1401.4
GTEX-14ASI-0011-R8b-SM-5S2UB
60-69 years, male
1247.4
GTEX-QVUS-0011-R8A-SM-3GAD7
60-69 years, female
1178.3
GTEX-13FXS-0011-R8a-SM-5J1MN
50-59 years, male
1082.8
GTEX-11OF3-0011-R8b-SM-57WCS
60-69 years, male
881.6
GTEX-T6MN-0011-R8A-SM-32QP3
50-59 years, male
707.2
GTEX-13O3Q-0011-R8b-SM-5KM2J
50-59 years, male
700.4
GTEX-13QIC-0011-R8b-SM-5O9CV
60-69 years, female
632.7
GTEX-1445S-0011-R8a-SM-5PNWX
60-69 years, male
617.6
GTEX-13SLW-0011-R8b-SM-5SI64
70-79 years, male
589.3
GTEX-X4XX-0011-R8B-SM-46MWM
60-69 years, male
566.8
GTEX-13CIG-0011-R8b-SM-5LZX5
50-59 years, male
562.0
GTEX-13N1W-0011-R8a-SM-5MR56
70-79 years, male
524.4
GTEX-13RTJ-0011-R8b-SM-5O9DL
60-69 years, male
516.7
GTEX-13NZA-0011-R8b-SM-5KM2Q
60-69 years, male
501.5
GTEX-NPJ8-0011-R8a-SM-2HMLG
40-49 years, male
458.8
GTEX-13OW6-0011-R8a-SM-5L3GF
50-59 years, male
457.1
GTEX-13CF2-0011-R8b-SM-5IJCX
60-69 years, male
445.1
GTEX-13G51-0011-R8b-SM-5LZZ4
60-69 years, male
440.3
GTEX-12WSM-0011-R8a-SM-5DUWJ
60-69 years, male
408.9
GTEX-13X6K-0011-R8b-SM-5PNZ4
60-69 years, female
402.3
GTEX-13OW7-0011-R8b-SM-5L3HR
50-59 years, male
401.6
GTEX-11WQC-0011-R8b-SM-57WCH
60-69 years, male
382.3
GTEX-WHSE-0011-R8A-SM-3P5Z1
20-29 years, male
372.7
GTEX-1313W-0011-R8a-SM-5DUVM
50-59 years, female
367.7
GTEX-13JVG-0011-R8a-SM-5KM3E
60-69 years, male
343.7
GTEX-144GL-0011-R8a-SM-5Q5B1
50-59 years, male
338.6
GTEX-1399T-0011-R8b-SM-5IJD8
60-69 years, male
315.3
GTEX-XMD1-0011-R8A-SM-4AT48
60-69 years, male
281.5
GTEX-13SLX-0011-R8b-SM-5PNWZ
50-59 years, female
273.4
GTEX-139TS-0011-R8a-SM-5J1NP
60-69 years, male
263.5
GTEX-P44H-0011-R8A-SM-2XCEL
40-49 years, male
259.7
GTEX-PWO3-0011-R8A-SM-2I5GD
60-69 years, female
244.1
GTEX-Z93S-0011-R8a-SM-4RGNL
50-59 years, male
242.6
GTEX-RU72-0011-R8A-SM-2TF61
50-59 years, female
241.5
GTEX-X585-0011-R8A-SM-46MUX
50-59 years, male
238.1
GTEX-R55E-0011-R8A-SM-2TC66
20-29 years, male
231.4
GTEX-13NYB-0011-R8a-SM-5KM4R
40-49 years, male
230.7
GTEX-ZVZQ-0011-R8a-SM-51MR5
60-69 years, female
225.0
GTEX-13IVO-0011-R8a-SM-5L3DY
70-79 years, male
216.7
GTEX-13OW5-0011-R8a-SM-5L3GQ
60-69 years, male
210.1
GTEX-145LU-0011-R8b-SM-5PNZG
50-59 years, male
207.9
GTEX-13OVH-0011-R8b-SM-5MR35
70-79 years, male
204.9
GTEX-WZTO-0011-R8A-SM-4E3II
40-49 years, male
200.6
GTEX-12ZZX-0011-R8a-SM-5DUW8
40-49 years, female
195.7
GTEX-14753-0011-R8b-SM-5S2U1
60-69 years, male
188.5
GTEX-TSE9-0011-R8A-SM-3DB7R
60-69 years, female
183.3
GTEX-11ONC-0011-R8b-SM-5NQ87
60-69 years, male
182.8
GTEX-ZDXO-0011-R8a-SM-4WWD7
60-69 years, male
180.7
GTEX-NPJ7-0011-R8a-SM-2I3G2
60-69 years, female
156.1
GTEX-147F4-0011-R8b-SM-5S2UN
50-59 years, male
153.0
GTEX-13O3O-0011-R8b-SM-5LUAL
60-69 years, female
140.5
GTEX-13OVJ-0011-R8b-SM-5L3FS
50-59 years, female
132.4
GTEX-XOTO-0011-R8A-SM-4B65J
50-59 years, male
129.9
GTEX-YJ89-0011-R8b-SM-4SOK8
60-69 years, male
129.9
GTEX-YFC4-0011-R8a-SM-4SOK3
40-49 years, female
124.9
GTEX-ZVT3-0011-R8b-SM-57WDJ
60-69 years, female
120.1
GTEX-11WQK-0011-R8a-SM-5BC7C
50-59 years, male
117.2
GTEX-13PDP-0011-R8b-SM-5O9CS
60-69 years, male
112.9
GTEX-13OVL-0011-R8a-SM-5L3HH
50-59 years, male
112.8
GTEX-11ZTS-0011-R8a-SM-57WDI
60-69 years, female
106.9
GTEX-13NYS-0011-R8a-SM-5MR5H
60-69 years, male
106.6
GTEX-X261-0011-R8A-SM-4E3I5
50-59 years, male
104.8
GTEX-N7MT-0011-R8a-SM-2I5GU
60-69 years, female
104.0
GTEX-ZXG5-0011-R8a-SM-57WD1
60-69 years, male
103.1
GTEX-Q2AG-0011-R8A-SM-2HMK5
40-49 years, female
93.2
GTEX-13FLV-0011-R8a-SM-5LZZE
50-59 years, male
85.4
GTEX-ZAB4-0011-R8b-SM-4SOKF
40-49 years, male
83.6
GTEX-13NZ8-0011-R8b-SM-5KM48
60-69 years, female
74.5
GTEX-131XW-0011-R8a-SM-5DUWY
50-59 years, female
64.7
GTEX-132Q8-0011-R8b-SM-5DUWX
60-69 years, male
55.4
GTEX-145LS-0011-R8b-SM-5PNXA
60-69 years, female
51.9
GTEX-13OW8-0011-R8a-SM-5L3G5
60-69 years, male
49.6
GTEX-T5JC-0011-R8A-SM-32PLM
20-29 years, male
48.8
GTEX-S7SE-0011-R8A-SM-2XCDG
50-59 years, male
47.0
GTEX-13X6J-0011-R8b-SM-5PNUA
50-59 years, male
43.9
GTEX-WWYW-0011-R8A-SM-3NB3S
50-59 years, female
43.4
GTEX-13FLW-0011-R8b-SM-5J1MZ
50-59 years, male
43.2
GTEX-ZF28-0011-R8a-SM-4WWFW
60-69 years, male
33.8
GTEX-11H98-0011-R8a-SM-5NQ8V
50-59 years, male
32.6
GTEX-QVJO-0011-R8A-SM-447C7
60-69 years, female
32.6
GTEX-WVLH-0011-R8A-SM-3MJFC
50-59 years, male
27.9
GTEX-X4XY-0011-R8A-SM-46MVC
60-69 years, male
27.3
GTEX-NL3H-0011-R8a-SM-5S2VF
60-69 years, male
25.2
GTEX-ZUA1-0011-R8b-SM-51MST
40-49 years, male
24.7
GTEX-N7MS-0011-R8a-SM-2YUMK
60-69 years, male
24.2
GTEX-131XH-0011-R8a-SM-5EGLL
50-59 years, male
20.6
GTEX-13X6I-0011-R8a-SM-5PNZF
60-69 years, male
20.5
GTEX-11GSP-0011-R8b-SM-5NQ79
60-69 years, female
20.0
GTEX-13QJC-0011-R8b-SM-5S2U6
60-69 years, female
18.8
GTEX-12WSA-0011-R8a-SM-5P9EX
60-69 years, male
17.2
GTEX-QMR6-0011-R8A-SM-32PKJ
50-59 years, male
16.0
GTEX-11ZUS-0011-R8a-SM-5BC73
30-39 years, male
15.0
GTEX-RVPU-0011-R8A-SM-5SI8I
50-59 years, male
12.4
GTEX-145MH-0011-R8a-SM-5PNUL
50-59 years, male
5.2
Show all
HYPOTHALAMUS - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.