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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Cells in tubules: 60 Cells in glomeruli: 20 Fibroblasts: 5 Other cell types: 15
Female, age 67
Sample 2 TPM: 342.5
Cell types%
Cells in tubules: 70 Cells in glomeruli: 15 Fibroblasts: 10 Other cell types: 5
Female, age 55
Sample 3 TPM: 213.4
Cell types%
Cells in tubules: 80 Cells in glomeruli: 10 Fibroblasts: 5 Other cell types: 5
Male, age 46
Sample 4 TPM: 389.1
Cell types%
Cells in tubules: 60 Cells in glomeruli: 25 Fibroblasts: 5 Other cell types: 10
Female, age 57
Sample 5 TPM: 160.9
Cell types%
Cells in tubules: 60 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 20
Male, age 78
Sample 6 TPM: 354.8
Cell types%
Cells in tubules: 65 Cells in glomeruli: 10 Fibroblasts: 5 Other cell types: 20
Male, age 73
Sample 7 TPM: 463.7
Cell types%
Cells in tubules: 60 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 20
Female, age 59
Sample 8 TPM: 406
Cell types%
Cells in tubules: 65 Cells in glomeruli: 10 Fibroblasts: 10 Other cell types: 15
Female, age 48
Sample 9 TPM: 295.8
Cell types%
Cells in tubules: 60 Cells in glomeruli: 5 Fibroblasts: 10 Other cell types: 25
KIDNEY - GTEx RNA-seqi
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 200.0
Min RPKM: 14.4
Std RPKM: 47.5
Median RPKM: 80.6
GTEX-145MN-0326-SM-5QGQI
30-39 years, male
200.0
GTEX-QDVN-1626-SM-48TZC
50-59 years, male
198.8
GTEX-1497J-0826-SM-5NQAJ
60-69 years, male
169.3
GTEX-P4QS-1126-SM-3NMD5
60-69 years, male
151.8
GTEX-13NYB-1726-SM-5N9G2
40-49 years, male
145.6
GTEX-XPVG-0526-SM-4B65N
50-59 years, male
145.5
GTEX-ZYFG-1626-SM-5GZYY
60-69 years, female
137.3
GTEX-UPIC-1126-SM-4IHLO
20-29 years, female
120.6
GTEX-Y5V6-2026-SM-5IFHO
60-69 years, male
120.4
GTEX-QLQW-1626-SM-4R1K1
30-39 years, male
117.3
GTEX-ZLFU-0926-SM-5P9F8
40-49 years, male
104.8
GTEX-N7MS-1626-SM-3LK5F
60-69 years, male
104.1
GTEX-ZVZP-0926-SM-5GIDB
50-59 years, male
101.7
GTEX-12696-0926-SM-5FQTV
60-69 years, male
87.9
GTEX-ZYT6-2226-SM-5GIC9
30-39 years, male
84.9
GTEX-ZC5H-1726-SM-5HL7X
40-49 years, female
83.9
GTEX-1399S-0526-SM-5IJG8
30-39 years, female
77.2
GTEX-13OVI-1126-SM-5KLZF
60-69 years, female
69.6
GTEX-13RTJ-2226-SM-5S2Q1
60-69 years, male
67.8
GTEX-13112-2126-SM-5GCO4
50-59 years, male
63.3
GTEX-11OF3-1326-SM-5N9FJ
60-69 years, male
62.1
GTEX-147F4-2626-SM-5Q5CS
50-59 years, male
60.3
GTEX-T5JC-1526-SM-4DM68
20-29 years, male
58.8
GTEX-13OVL-1826-SM-5KLZR
50-59 years, male
54.5
GTEX-12WSG-0826-SM-5EQ5A
50-59 years, female
51.8
GTEX-RN64-1626-SM-48FD7
50-59 years, male
48.1
GTEX-13OW6-1826-SM-5N9F9
50-59 years, male
47.1
GTEX-11GS4-2326-SM-5A5KS
60-69 years, male
44.9
GTEX-11TTK-1926-SM-5PNW8
60-69 years, female
42.8
GTEX-13O1R-2526-SM-5N9FW
60-69 years, male
42.3
GTEX-NPJ8-2226-SM-3TW8D
40-49 years, male
29.3
GTEX-ZYFD-1526-SM-5NQ7T
50-59 years, male
14.4
Show all
KIDNEY - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.
The Human Protein Atlas project is funded
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