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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA027873
Moderate to strong membranous and cytoplasmic positivity was observed in renal tubuli, exocrine pancreas, bile duct cells and lymphoid cells outside reaction centra. Placental trophoblasts showed strong nuclear staining. Remaining normal cells were either negative or weakly stained.
HPA042128
Strong nuclear staining was observed in subsets of lymphoid non-germinal center cells and a fraction of hematopoietic cells. Lung macrophages, colon, adrenal gland, fallopian tube, testis and heart showed weak to moderate cytoplasmic positivity. Remaining normal tissues were negative.
HPA049883
Most of the normal cells displayed weak to moderate cytoplasmic and/or nuclear positivity. Soft tissue, neuronal cells and urothelium cells were negative.
HPA051156
Most normal tissues displayed weak to moderate cytoplasmic positivity. Additional strong membranous staining was exhibited in ciliated cells. Lung, liver, pancreas, glial cells, neurons, smooth muscle and adipocytes were negative.
CAB003860
Strong cytoplasmic and nuclear immunoreactivity was observed in a subset of lymphoid cells and in glandular cells of breast. Remaining normal tissues were in general negative.
The Human Protein Atlas project is funded
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