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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody HPA020137
Glial cells
Medium
Neuronal cells
Low
Neuronal projections
High
Synapses
Not detected
HYPOTHALAMUS - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 17.6
Min RPKM: 1.2
Std RPKM: 3.7
Median RPKM: 6.9
GTEX-QMR6-0011-R8A-SM-32PKJ
50-59 years, male
17.6
GTEX-X585-0011-R8A-SM-46MUX
50-59 years, male
16.5
GTEX-QVUS-0011-R8A-SM-3GAD7
60-69 years, female
15.8
GTEX-13X6K-0011-R8b-SM-5PNZ4
60-69 years, female
14.4
GTEX-13O3Q-0011-R8b-SM-5KM2J
50-59 years, male
14.2
GTEX-NPJ8-0011-R8a-SM-2HMLG
40-49 years, male
14.1
GTEX-13OW6-0011-R8a-SM-5L3GF
50-59 years, male
13.6
GTEX-WZTO-0011-R8A-SM-4E3II
40-49 years, male
13.1
GTEX-1399T-0011-R8b-SM-5IJD8
60-69 years, male
12.9
GTEX-13G51-0011-R8b-SM-5LZZ4
60-69 years, male
12.4
GTEX-T5JC-0011-R8A-SM-32PLM
20-29 years, male
12.4
GTEX-P44H-0011-R8A-SM-2XCEL
40-49 years, male
12.3
GTEX-S7SE-0011-R8A-SM-2XCDG
50-59 years, male
12.0
GTEX-13OW7-0011-R8b-SM-5L3HR
50-59 years, male
11.9
GTEX-11OF3-0011-R8b-SM-57WCS
60-69 years, male
11.8
GTEX-13RTJ-0011-R8b-SM-5O9DL
60-69 years, male
11.7
GTEX-13NYB-0011-R8a-SM-5KM4R
40-49 years, male
11.5
GTEX-13SLW-0011-R8b-SM-5SI64
70-79 years, male
11.5
GTEX-14ASI-0011-R8b-SM-5S2UB
60-69 years, male
11.5
GTEX-13NZA-0011-R8b-SM-5KM2Q
60-69 years, male
11.2
GTEX-R55F-0011-R8A-SM-2TF4F
50-59 years, male
11.2
GTEX-13CIG-0011-R8b-SM-5LZX5
50-59 years, male
11.1
GTEX-13FXS-0011-R8a-SM-5J1MN
50-59 years, male
10.9
GTEX-12ZZX-0011-R8a-SM-5DUW8
40-49 years, female
10.7
GTEX-13N1W-0011-R8a-SM-5MR56
70-79 years, male
10.5
GTEX-NPJ7-0011-R8a-SM-2I3G2
60-69 years, female
10.5
GTEX-1313W-0011-R8a-SM-5DUVM
50-59 years, female
10.0
GTEX-13QIC-0011-R8b-SM-5O9CV
60-69 years, female
10.0
GTEX-PWO3-0011-R8A-SM-2I5GD
60-69 years, female
9.7
GTEX-X4XX-0011-R8B-SM-46MWM
60-69 years, male
9.7
GTEX-RU72-0011-R8A-SM-2TF61
50-59 years, female
9.2
GTEX-11ZUS-0011-R8a-SM-5BC73
30-39 years, male
9.1
GTEX-13CF2-0011-R8b-SM-5IJCX
60-69 years, male
9.0
GTEX-Z93S-0011-R8a-SM-4RGNL
50-59 years, male
9.0
GTEX-131XH-0011-R8a-SM-5EGLL
50-59 years, male
8.6
GTEX-TSE9-0011-R8A-SM-3DB7R
60-69 years, female
8.4
GTEX-YFC4-0011-R8a-SM-4SOK3
40-49 years, female
8.2
GTEX-13OVH-0011-R8b-SM-5MR35
70-79 years, male
8.0
GTEX-WHSE-0011-R8A-SM-3P5Z1
20-29 years, male
8.0
GTEX-11ONC-0011-R8b-SM-5NQ87
60-69 years, male
7.9
GTEX-ZDXO-0011-R8a-SM-4WWD7
60-69 years, male
7.9
GTEX-145LS-0011-R8b-SM-5PNXA
60-69 years, female
7.6
GTEX-11WQC-0011-R8b-SM-57WCH
60-69 years, male
7.5
GTEX-X261-0011-R8A-SM-4E3I5
50-59 years, male
7.5
GTEX-145LU-0011-R8b-SM-5PNZG
50-59 years, male
7.3
GTEX-NL4W-0011-R8a-SM-2I3G4
50-59 years, male
7.2
GTEX-ZUA1-0011-R8b-SM-51MST
40-49 years, male
7.1
GTEX-145MH-0011-R8a-SM-5PNUL
50-59 years, male
6.9
GTEX-QVJO-0011-R8A-SM-447C7
60-69 years, female
6.9
GTEX-13SLX-0011-R8b-SM-5PNWZ
50-59 years, female
6.7
GTEX-12WSM-0011-R8a-SM-5DUWJ
60-69 years, male
6.6
GTEX-XOTO-0011-R8A-SM-4B65J
50-59 years, male
6.5
GTEX-T6MN-0011-R8A-SM-32QP3
50-59 years, male
6.4
GTEX-ZVZQ-0011-R8a-SM-51MR5
60-69 years, female
6.4
GTEX-13FLV-0011-R8a-SM-5LZZE
50-59 years, male
6.3
GTEX-R55E-0011-R8A-SM-2TC66
20-29 years, male
6.2
GTEX-147F4-0011-R8b-SM-5S2UN
50-59 years, male
6.1
GTEX-13IVO-0011-R8a-SM-5L3DY
70-79 years, male
6.0
GTEX-13PDP-0011-R8b-SM-5O9CS
60-69 years, male
6.0
GTEX-ZVT3-0011-R8b-SM-57WDJ
60-69 years, female
6.0
GTEX-13OW5-0011-R8a-SM-5L3GQ
60-69 years, male
5.9
GTEX-13X6J-0011-R8b-SM-5PNUA
50-59 years, male
5.9
GTEX-144GL-0011-R8a-SM-5Q5B1
50-59 years, male
5.9
GTEX-13JVG-0011-R8a-SM-5KM3E
60-69 years, male
5.8
GTEX-13O3O-0011-R8b-SM-5LUAL
60-69 years, female
5.8
GTEX-Q2AG-0011-R8A-SM-2HMK5
40-49 years, female
5.8
GTEX-13OVL-0011-R8a-SM-5L3HH
50-59 years, male
5.5
GTEX-132Q8-0011-R8b-SM-5DUWX
60-69 years, male
5.2
GTEX-N7MT-0011-R8a-SM-2I5GU
60-69 years, female
5.2
GTEX-ZAB4-0011-R8b-SM-4SOKF
40-49 years, male
5.1
GTEX-ZXG5-0011-R8a-SM-57WD1
60-69 years, male
5.1
GTEX-13FLW-0011-R8b-SM-5J1MZ
50-59 years, male
4.7
GTEX-13X6I-0011-R8a-SM-5PNZF
60-69 years, male
4.5
GTEX-YJ89-0011-R8b-SM-4SOK8
60-69 years, male
4.5
GTEX-11ZTS-0011-R8a-SM-57WDI
60-69 years, female
4.4
GTEX-13NYS-0011-R8a-SM-5MR5H
60-69 years, male
4.4
GTEX-139TS-0011-R8a-SM-5J1NP
60-69 years, male
4.3
GTEX-13OVJ-0011-R8b-SM-5L3FS
50-59 years, female
4.3
GTEX-WVLH-0011-R8A-SM-3MJFC
50-59 years, male
4.3
GTEX-12WSA-0011-R8a-SM-5P9EX
60-69 years, male
4.2
GTEX-XMD1-0011-R8A-SM-4AT48
60-69 years, male
4.1
GTEX-WWYW-0011-R8A-SM-3NB3S
50-59 years, female
4.0
GTEX-13NZ8-0011-R8b-SM-5KM48
60-69 years, female
3.7
GTEX-11GSP-0011-R8b-SM-5NQ79
60-69 years, female
3.6
GTEX-13OW8-0011-R8a-SM-5L3G5
60-69 years, male
3.2
GTEX-1445S-0011-R8a-SM-5PNWX
60-69 years, male
3.1
GTEX-11H98-0011-R8a-SM-5NQ8V
50-59 years, male
3.0
GTEX-13QJC-0011-R8b-SM-5S2U6
60-69 years, female
3.0
GTEX-N7MS-0011-R8a-SM-2YUMK
60-69 years, male
3.0
GTEX-ZF28-0011-R8a-SM-4WWFW
60-69 years, male
2.8
GTEX-131XW-0011-R8a-SM-5DUWY
50-59 years, female
2.6
GTEX-11WQK-0011-R8a-SM-5BC7C
50-59 years, male
1.9
GTEX-X4XY-0011-R8A-SM-46MVC
60-69 years, male
1.7
GTEX-14753-0011-R8b-SM-5S2U1
60-69 years, male
1.6
GTEX-NL3H-0011-R8a-SM-5S2VF
60-69 years, male
1.6
GTEX-RVPU-0011-R8A-SM-5SI8I
50-59 years, male
1.2
Show all
HYPOTHALAMUS - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.