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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA041702
Normal tissues generally displayed moderate granular cytoplasmic positivity with additional nuclear staining in several tissues. Leydig cells, renal tubules, duodenum and lung were strongly positive. The spleen was negative.
HPA041727
Moderate granular cytoplasmic staining in most tissues. Additional nuclear positivity was observed in several tissues. Strong staining was observed in macrophages, kidney, trophoblastic cells, adrenal gland and the basal cell layer in squamous epithelia. Membranous positivity was observed in gastrointestinal glands, gallbladder, fallopian tube and thyroid.
The Human Protein Atlas project is funded
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