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The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.
h
m
l
n
RNA expressioni
RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.
The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.
Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.
The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody HPA071892
Glial cells
Not detected
Neuronal cells
High
Neuronal projections
High
Synapses
Not detected
Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
- Antibody CAB025318
Glial cells
Not detected
Neuronal cells
High
Neuronal projections
High
Synapses
Not detected
HYPOTHALAMUS - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.
Max RPKM: 22829.4
Min RPKM: 0.0
Std RPKM: 3554.5
Median RPKM: 154.5
GTEX-X261-0011-R8A-SM-4E3I5
50-59 years, male
22829.4
GTEX-WVLH-0011-R8A-SM-3MJFC
50-59 years, male
15669.5
GTEX-13G51-0011-R8b-SM-5LZZ4
60-69 years, male
14197.5
GTEX-QVUS-0011-R8A-SM-3GAD7
60-69 years, female
10605.1
GTEX-13OW5-0011-R8a-SM-5L3GQ
60-69 years, male
8161.4
GTEX-WHSE-0011-R8A-SM-3P5Z1
20-29 years, male
7822.1
GTEX-R55F-0011-R8A-SM-2TF4F
50-59 years, male
7455.6
GTEX-NL4W-0011-R8a-SM-2I3G4
50-59 years, male
6551.0
GTEX-RU72-0011-R8A-SM-2TF61
50-59 years, female
4676.0
GTEX-13IVO-0011-R8a-SM-5L3DY
70-79 years, male
4363.0
GTEX-13RTJ-0011-R8b-SM-5O9DL
60-69 years, male
3445.3
GTEX-13O3Q-0011-R8b-SM-5KM2J
50-59 years, male
3339.2
GTEX-Q2AG-0011-R8A-SM-2HMK5
40-49 years, female
3285.0
GTEX-13JVG-0011-R8a-SM-5KM3E
60-69 years, male
2829.8
GTEX-139TS-0011-R8a-SM-5J1NP
60-69 years, male
2688.9
GTEX-12WSM-0011-R8a-SM-5DUWJ
60-69 years, male
2587.9
GTEX-11OF3-0011-R8b-SM-57WCS
60-69 years, male
2537.4
GTEX-ZVT3-0011-R8b-SM-57WDJ
60-69 years, female
2361.5
GTEX-13OW8-0011-R8a-SM-5L3G5
60-69 years, male
2202.3
GTEX-13PDP-0011-R8b-SM-5O9CS
60-69 years, male
2013.9
GTEX-145LU-0011-R8b-SM-5PNZG
50-59 years, male
1834.2
GTEX-ZXG5-0011-R8a-SM-57WD1
60-69 years, male
1788.1
GTEX-13O3O-0011-R8b-SM-5LUAL
60-69 years, female
1682.6
GTEX-13FXS-0011-R8a-SM-5J1MN
50-59 years, male
1542.7
GTEX-11WQC-0011-R8b-SM-57WCH
60-69 years, male
1504.6
GTEX-T6MN-0011-R8A-SM-32QP3
50-59 years, male
1394.3
GTEX-13SLX-0011-R8b-SM-5PNWZ
50-59 years, female
1197.3
GTEX-13OW7-0011-R8b-SM-5L3HR
50-59 years, male
893.0
GTEX-13OW6-0011-R8a-SM-5L3GF
50-59 years, male
790.9
GTEX-13CIG-0011-R8b-SM-5LZX5
50-59 years, male
769.8
GTEX-1313W-0011-R8a-SM-5DUVM
50-59 years, female
688.4
GTEX-XOTO-0011-R8A-SM-4B65J
50-59 years, male
647.1
GTEX-13NYS-0011-R8a-SM-5MR5H
60-69 years, male
641.3
GTEX-YJ89-0011-R8b-SM-4SOK8
60-69 years, male
487.1
GTEX-14753-0011-R8b-SM-5S2U1
60-69 years, male
480.3
GTEX-S7SE-0011-R8A-SM-2XCDG
50-59 years, male
410.5
GTEX-13NYB-0011-R8a-SM-5KM4R
40-49 years, male
370.2
GTEX-145LS-0011-R8b-SM-5PNXA
60-69 years, female
332.0
GTEX-X4XY-0011-R8A-SM-46MVC
60-69 years, male
328.5
GTEX-R55E-0011-R8A-SM-2TC66
20-29 years, male
308.8
GTEX-14ASI-0011-R8b-SM-5S2UB
60-69 years, male
270.8
GTEX-13NZ8-0011-R8b-SM-5KM48
60-69 years, female
241.4
GTEX-13OVH-0011-R8b-SM-5MR35
70-79 years, male
209.6
GTEX-13SLW-0011-R8b-SM-5SI64
70-79 years, male
196.6
GTEX-13OVL-0011-R8a-SM-5L3HH
50-59 years, male
194.1
GTEX-13CF2-0011-R8b-SM-5IJCX
60-69 years, male
187.7
GTEX-13X6K-0011-R8b-SM-5PNZ4
60-69 years, female
177.7
GTEX-1445S-0011-R8a-SM-5PNWX
60-69 years, male
156.4
GTEX-147F4-0011-R8b-SM-5S2UN
50-59 years, male
152.5
GTEX-144GL-0011-R8a-SM-5Q5B1
50-59 years, male
52.5
GTEX-13QIC-0011-R8b-SM-5O9CV
60-69 years, female
35.3
GTEX-QMR6-0011-R8A-SM-32PKJ
50-59 years, male
31.5
GTEX-12ZZX-0011-R8a-SM-5DUW8
40-49 years, female
28.6
GTEX-XMD1-0011-R8A-SM-4AT48
60-69 years, male
21.0
GTEX-PWO3-0011-R8A-SM-2I5GD
60-69 years, female
20.7
GTEX-132Q8-0011-R8b-SM-5DUWX
60-69 years, male
19.9
GTEX-131XW-0011-R8a-SM-5DUWY
50-59 years, female
15.3
GTEX-T5JC-0011-R8A-SM-32PLM
20-29 years, male
14.0
GTEX-1399T-0011-R8b-SM-5IJD8
60-69 years, male
13.9
GTEX-13NZA-0011-R8b-SM-5KM2Q
60-69 years, male
12.4
GTEX-131XH-0011-R8a-SM-5EGLL
50-59 years, male
10.0
GTEX-ZAB4-0011-R8b-SM-4SOKF
40-49 years, male
8.3
GTEX-ZVZQ-0011-R8a-SM-51MR5
60-69 years, female
7.0
GTEX-11ZTS-0011-R8a-SM-57WDI
60-69 years, female
5.4
GTEX-P44H-0011-R8A-SM-2XCEL
40-49 years, male
5.1
GTEX-11ZUS-0011-R8a-SM-5BC73
30-39 years, male
3.9
GTEX-11ONC-0011-R8b-SM-5NQ87
60-69 years, male
3.6
GTEX-X585-0011-R8A-SM-46MUX
50-59 years, male
3.6
GTEX-Z93S-0011-R8a-SM-4RGNL
50-59 years, male
3.6
GTEX-YFC4-0011-R8a-SM-4SOK3
40-49 years, female
3.2
GTEX-13X6I-0011-R8a-SM-5PNZF
60-69 years, male
2.9
GTEX-QVJO-0011-R8A-SM-447C7
60-69 years, female
2.6
GTEX-11WQK-0011-R8a-SM-5BC7C
50-59 years, male
1.4
GTEX-X4XX-0011-R8B-SM-46MWM
60-69 years, male
1.4
GTEX-13FLV-0011-R8a-SM-5LZZE
50-59 years, male
1.3
GTEX-13X6J-0011-R8b-SM-5PNUA
50-59 years, male
1.2
GTEX-WWYW-0011-R8A-SM-3NB3S
50-59 years, female
1.1
GTEX-11H98-0011-R8a-SM-5NQ8V
50-59 years, male
1.0
GTEX-13N1W-0011-R8a-SM-5MR56
70-79 years, male
1.0
GTEX-ZDXO-0011-R8a-SM-4WWD7
60-69 years, male
0.8
GTEX-ZF28-0011-R8a-SM-4WWFW
60-69 years, male
0.8
GTEX-13QJC-0011-R8b-SM-5S2U6
60-69 years, female
0.5
GTEX-WZTO-0011-R8A-SM-4E3II
40-49 years, male
0.5
GTEX-N7MT-0011-R8a-SM-2I5GU
60-69 years, female
0.4
GTEX-13OVJ-0011-R8b-SM-5L3FS
50-59 years, female
0.3
GTEX-NPJ7-0011-R8a-SM-2I3G2
60-69 years, female
0.3
GTEX-13FLW-0011-R8b-SM-5J1MZ
50-59 years, male
0.2
GTEX-NPJ8-0011-R8a-SM-2HMLG
40-49 years, male
0.1
GTEX-11GSP-0011-R8b-SM-5NQ79
60-69 years, female
0.0
GTEX-12WSA-0011-R8a-SM-5P9EX
60-69 years, male
0.0
GTEX-145MH-0011-R8a-SM-5PNUL
50-59 years, male
0.0
GTEX-N7MS-0011-R8a-SM-2YUMK
60-69 years, male
0.0
GTEX-NL3H-0011-R8a-SM-5S2VF
60-69 years, male
0.0
GTEX-RVPU-0011-R8A-SM-5SI8I
50-59 years, male
0.0
GTEX-TSE9-0011-R8A-SM-3DB7R
60-69 years, female
0.0
GTEX-ZUA1-0011-R8b-SM-51MST
40-49 years, male
0.0
Show all
HYPOTHALAMUS - FANTOM5 CAGEi
Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.