Somatostatin (SST) - Marker for pancreatic delta-cells

Somatostatin is a peptide hormone found in the stomach, intestines, in certain neurons and in delta cells of the pancreatic islets of Langerhans. Somatostatin binds to somatostatin receptors and regulates (inhibits) the release of insulin and glucagon. Somatostatin also affects neurotransmission and cell proliferation.