The cell cycle is a fundamental process over which the cell grows and divides. This highly regulated series of events is known to be an important contributor to variations in protein and RNA expression between individual cells. Today we are releasing version 20.1 of the Human Protein Atlas (HPA), adding new data to the Cell Atlas, which allows detailed exploration of protein and RNA expression in relation to cell cycle progression...Read more

Facets of individual-specific health signatures determined from longitudinal plasma proteome profilingProteins that circulate in human blood can provide important information about health or disease states of an individual. To gain insight into personal baselines and how protein levels vary over time, researchers within the HPA have studied the plasma proteomes of clinically healthy individuals during one year...Read more

An important aspect of precision medicine is to probe the stability in molecular profiles among healthy individuals over time. This has been published in an article in Nature Communications (Tebani et al)...Read more

Spermatogenesis is the process where sperm are made, and it involves thousands of genes and proteins that are activated and repressed. The function of a large proportion of these genes and proteins remains unknown and testis harbors many "missing proteins" (MPs)...Read more

Over time, cells accumulate DNA mutations, that if transcribed and translated influence gene expression and/or function of the protein. The increasing number mutations in eg. genes that control cell division eventually lead formation of tumor...Read more